Evaluation of environmental contamination with cytotoxic drugs in the hospital is the one of the fundamental requirements to ensure the safety of all healthcare professionals. Safe handling procedures should be closely monitored in all areas where antineoplastic drugs are delivered, stored, prepared, administered and disposed of. Over the past few years environmental contamination with cytotoxic drugs in hospitals units has been reported in several publications. However, detailed information on surface contamination with antineoplastic drugs in European hospitals in areas where these drugs are handled, is still limited. Therefore, the European Society of Oncology Pharmacy (ESOP) undertook the first independent, multi-centre, pan European study, involving over a dozen hospitals, to measure the current state of cytotoxic contamination in the workplace.  This project is called MASHA – Research about Environmental Contamination by Cytotoxicsand Management of Safe Handling Procedures.

The study was designed to investigate any possible weak points during drug preparation, transportation and application, and during the disposal of medical devices after treatment. Lessons learned would be used to create international guidelines for the handling of antineoplastic drugs. The study was carried out at 15 hospitals in Europe in order to observe a broad variety of procedures and cases. The results of the MASHA project will be presented during the European Conference Oncology Pharmacy (ECOP) in Dubrovnik, 20 May 2016.

ESOP- Project Language
Monitoring of surfaces contamination with antineoplastic drugs in preparation
and administration areas
About the ESOP Project


Sponsored by:

  • Berner International GmbH
  • B. Braun Melsungen AG
  • CODAN pvb Medical GmbH
  • TEVA GmbH